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2 765 545

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IPC

C07D207/50(2006-01-01)

A61K31/4015(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2020133367, 2020-10-12

(24)

Start date

2020-10-12

(22)

Actual filing date

2020-10-12

(45)

Published

2022-02-01

(72)

Inventor

Zykova Svetlana SergeevnaBojchuk Sergej VasilevichIgidov Nazim MusabekovichGalembikova Ajgul RafikovnaAukhadieva Aida MaratovnaBikinieva Firyuza FanisovnaNurgatina Ilmira IlyazovnaGankova Kseniya LeonidovnaShustov Maksim Vadimovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennaya Farmatsevticheskaya Akademiya» Ministerstva Zdravookhraneniya Rossijskoj FederatsiiFederalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet» Ministerstva Zdravookhraneniya Rossijskoj Federatsii

2-AMINO-1-BENZAMIDO-5-(3,3-DIMETHYL-2-OXOBUTYLIDENE)-4-OXO-4,5-DIHYDRO-1H-PYRROL-3-CARBOXAMIDE CAUSING IRREGULARITIES IN THE PHASES OF THE CELL CYCLE AND EXHIBITING CYTOTOXIC ACTIVITY AGAINST SOFT TISSUE SARCOMAS AND GASTROINTESTINAL STROMAL TUMOURS (GIST) Russian patent published in 2022 - IPC C07D207/50 A61K31/4015 A61P35/00

Abstract RU 2765545 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to an application of 2-amino-1-benzamido-5-(3,3-dimethyl-2-oxobutylidene)-4-oxo-4,5-dihydro-1H-pyrrol-3-carboxamide I by the formula below for producing an anti-tumour medicinal product.

EFFECT: compound exhibits cytotoxic activity against soft tissue sarcomas and gastrointestinal stromal tumours.

1 cl, 3 dwg, 2 tbl

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RU 2 765 545 C1

Authors

Zykova Svetlana Sergeevna

Bojchuk Sergej Vasilevich

Igidov Nazim Musabekovich

Galembikova Ajgul Rafikovna

Aukhadieva Aida Maratovna

Bikinieva Firyuza Fanisovna

Nurgatina Ilmira Ilyazovna

Gankova Kseniya Leonidovna

Shustov Maksim Vadimovich

Dates

2022-02-01—Published

2020-10-12—Filed