FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and is intended for use in medicine as a drug with antimicrobial properties. In particular, the invention relates to derivatives of 3-aminofuran-2(5H)-ones, specifically to 5-(4-chlorophenyl)-3-((4-chlorophenyl)amino)-5-(phenylthio)furan-2(5H)-one of formula 1.
EFFECT: providing pronounced antimicrobial activity with low toxicity.
1 cl, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| USE OF 5-(4-CHLOROPHENYL)-N-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)-1-ETHYL-1H-PYRAZOLE-3-CARBOXAMIDE AS AN ANTIMICROBIAL AGENT | 2023 |
|
RU2809149C1 |
| USE OF 4-(4-CHLOROPHENYL)-N-(3-CYANO-4,5,6,7-TETRAHYDROBEZO[b]THIOPHEN-2-YL)-3H-BENZO[b][1,4]DIAZEPINE-2-CARBOXAMIDE AS AN ANTIMICROBIAL AGENT | 2023 |
|
RU2809055C1 |
| (Z)-2-((4-R-5-R-3-(ETHOXYCARBONYL)THIOPHEN-2-YL)AMINO)-4-OXO-4-R-BUT-2-ENE ACIDS, HAVING ANTIMICROBIAL ACTIVITY | 2019 |
|
RU2722176C1 |
| USE OF 5-(4-METHYLPHENYL)-3-(METOXYIMINO)-3H-FURAN-2-ONE AS AN ANTI-MICROBIAL AGENT | 2022 |
|
RU2806263C2 |
| 5-PHENYL-2-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIEN-2-YL)IMINO-2H-FURAN-3-ONE, POSSESSING ANTIMICROBIAL AND ANALGETIC ACTIVITY | 2014 |
|
RU2560521C1 |
| AMIDE (E)-2-AMINO-4-OXO-5-(2-OXO-2-PHENYLETHYLIDENE)-1-(3-ETHOXYCARBONYL)-4,5,6-7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)4,5-DIHYDRO-1H-PYRROLE-3-CARBOXYLIC ACID, HAVING ANTIMICROBIAL ACTIVITY | 2020 |
|
RU2738405C1 |
| APPLICATION OF N-(2-OXO-5-(4-CHLOROPHENYL)FURAN-3(2H)-YLYDENE)-4-NITROBENZOHYDRAZIDE AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785782C1 |
| USE OF ETHYL-4-(4-HYDROXY-2-OXO-4-(THIOPHENE-2-YL)BUT-3-ENTHIOAMIDO)BENZOATE FOR TREATMENT OF DISEASES CAUSED BY GOLDEN STAPHYLOCOCCUS | 2022 |
|
RU2785779C1 |
| APPLICATION OF 2-[(3-(AMINOCARBONIL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]-4-OXO-4-(4-CHLOROPHENYL)BUT-2-ENOIC ACID IN AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785780C1 |
| (E)-4-((5-(4- BROMOPHENYL)-1-((2,4-DINITROPHENYL)AMINO)-2-OXO-1,2-DIHYDRO-3H-PYRROL-3-YLIDENE)AMINO)-1,5-DIMETHYL-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOLE-3-ONE, WITH ANTIMICROBIAL ACTIVITY | 2021 |
|
RU2776067C1 |
