FIELD: organic chemistry; pharmaceutics.
SUBSTANCE: invention relates to the field of organic chemistry and pharmaceutics, namely to the use of a new biologically active derivative of 2,4-dioxothiobutane acid amide. The use of ethyl-4-(4-hydroxy-2-oxo-4-(thiophene-yl)but-3-enthioamido)benzoate for the treatment of diseases caused by golden staphylococcus is disclosed.
EFFECT: provision of effective treatment of diseases caused by golden staphylococcus with low toxicity.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| (Z)-2-((4-R-5-R-3-(ETHOXYCARBONYL)THIOPHEN-2-YL)AMINO)-4-OXO-4-R-BUT-2-ENE ACIDS, HAVING ANTIMICROBIAL ACTIVITY | 2019 |
|
RU2722176C1 |
| USE OF ETHYL 5-METHYL-2-(((2Z,3Z)-3-(2-OXO-2-PHENYLYLIDENE)-3,4-DIHYDRO-2H-BENZO[b][1,4]THIAZINE-2-YLIDENE )AMION)THIOPHENE-3-CAROXYLATE AS AN ANTI-MICROBIAL AGENT AGAINST STAPHYLOCOCC AUREUS (S.AUREUS) AND ESCHERICHIA COLI (E.COLI) | 2023 |
|
RU2809159C1 |
| APPLICATION OF ANTIMICROBIAL AGENT FOR GOLDEN STAPHYLOCOCCUS WITH MULTIPLE DRUG RESISTANCE BASED ON 2-((4-R1-5-R2-3-(ETHOXICARBONYL)THIOPHENE-2-YL)AMINO-4-R3-OXO-ENOIC ACIDS | 2021 |
|
RU2763735C1 |
| 11,11-DIMETHYL-1-OXO-1,2,10,11-TETRAHYDROBENZO[h]PYRROLO-[2,1-a]-ISOQUINOLINE-2-SPIRO-2-(1-ARYL-3-AROYL-4-HYDROXY-5-OXO-2,5-DIHYDROPYRROLES) ELICITING ANTIBACTERIAL ACTIVITY AGAINST GRAM-POSITIVE MICROFLORA | 2005 |
|
RU2281286C1 |
| N-(2-BENZOTHIAZOLYL)AMIDE 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL)-2-BUTENOIC ACID HAVING ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTIVITY | 2008 |
|
RU2396262C2 |
| USE OF 4-(4-CHLOROPHENYL)-N-(3-CYANO-4,5,6,7-TETRAHYDROBEZO[b]THIOPHEN-2-YL)-3H-BENZO[b][1,4]DIAZEPINE-2-CARBOXAMIDE AS AN ANTIMICROBIAL AGENT | 2023 |
|
RU2809055C1 |
| AMIDE (E)-2-AMINO-4-OXO-5-(2-OXO-2-PHENYLETHYLIDENE)-1-(3-ETHOXYCARBONYL)-4,5,6-7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)4,5-DIHYDRO-1H-PYRROLE-3-CARBOXYLIC ACID, HAVING ANTIMICROBIAL ACTIVITY | 2020 |
|
RU2738405C1 |
| IZOPROPYLAMIDE OF 2-(BETA-2,4-DINITROPHENYLHYDRAZINO)CINHONINIC ACID, DEMONSTRATING ANTIMICROBIAL ACTIVITY | 2008 |
|
RU2364590C1 |
| APPLICATION OF ANTIFUNGAL AGENT BASED ON 2-((4-R1-5-R2-3-(ETHOXYCARBONYL)THIOPHENE-2-IL)AMINO)-4-OXO-4-R3-BUT-2-ENO ACIDS IN RELATION TO CANDIDA ALDICANS | 2021 |
|
RU2770598C1 |
| APPLICATION OF 2-[(3-(AMINOCARBONIL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]-4-OXO-4-(4-CHLOROPHENYL)BUT-2-ENOIC ACID IN AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785780C1 |
