USE OF SUBSTITUTED ESTERS OF (Z)-2-(2-(DIPHENYLMETHYLENE)HYDRAZINYL)-5,5-DIMETHYL-4-OXOHEX-2-ENOIC ACID AS AN ANTIBACTERIAL AND ANTIFUNGAL AGENT Russian patent published in 2022 - IPC C07C251/86 A61K31/15 A61P31/04 A61P31/10 

Abstract RU 2768761 C1

FIELD: chemistry.

SUBSTANCE: invention relates to use of substituted esters of (Z)-2-(2-(diphenylmethylene)hydrazinyl)-5,5-dimethyl-4-oxohex-2-enoic acid 1, 2 of structural formula I as an antibacterial and antifungal agent.

(I).

EFFECT: compounds having pronounced antibacterial and antifungal activity, as well as low toxicity are obtained.

1 cl, 2 tbl, 4 ex

Similar patents RU2768761C1

Title Year Author Number
N-(1-H-BENZO[d]IMIDAZOLE-2-yl)-2-(2-(DIPHENYLMETHYLENE)HYDRAZINYL)-5,5-DIMETHYL-4-OXOHEX-2-ENEAMIDE EXHIBITING ANALGESIC ACTIVITY 2021
  • Syutkina Alena Ivanovna
  • Igidov Nazim Musabekovich
  • Makhmudov Ramiz Ragibovich
RU2786673C1
FURAN-2-YLMETHYL-2-(2-(DIPHENYLMETHYLENE)HYDRAZINYL)-5,5-DIMETHYL-4-OXOHEX-2-ENOATE WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY 2021
  • Siutkina Alena Ivanovna
  • Igidov Nazim Musabekovich
  • Chashchina Svetlana Viktorovna
  • Shipilovskikh Sergei Aleksandrovich
  • Kizimova Irina Anatolevna
RU2784447C2
APPLICATION OF ANTIFUNGAL AGENT BASED ON 2-((4-R1-5-R2-3-(ETHOXYCARBONYL)THIOPHENE-2-IL)AMINO)-4-OXO-4-R3-BUT-2-ENO ACIDS IN RELATION TO CANDIDA ALDICANS 2021
  • Shipilovskikh Sergej Aleksandrovich
  • Rubtsov Aleksandr Evgenevich
  • Makhmudov Ramiz Ragibovich
  • Shipilovskikh Darya Aleksandrovna
  • Tkachenko Aleksandr Georgievich
  • Nesterova Larisa Yurevna
RU2770598C1
N-(2-THIAZOLYL)AMIDE OF 2-(2-OXO-3-INDOLINYLIDENE)HYDRAZINO-4-OXO-4-PHENYL-2-BUTENOIC ACID HAVING ANTIBACTERIAL AND ANALGESIC ACTIVITY 2008
  • Pulina Natal'Ja Alekseevna
  • Jushkov Vladimir Viktorovich
  • Sobin Fedor Vladimirovich
  • Odegova Tat'Jana Fedorovna
  • Vakhrin Mikhail Ivanovich
  • Jatsenko Konstantin Vjacheslavovich
  • Fedorenko Elena Nikolaevna
RU2401837C2
APPLICATION OF 4-ARYL-4-OXO-2-[2-(9H-FLUORENE-9-YLIDENE)HYDRAZONO] BUT-2-ENO ACIDS AS ANALGESICS 2021
  • Rubtsov Aleksandr Evgenevich
  • Makhmudov Ramiz Ragibovich
RU2771030C1
ETHYL ALCOHOL (5Z)-2-AMINO-5-[1-BROMO-2-(4-BROMOPHENYL)-2-OXO-ETHYLIDENE]-4-OXO-1H-4,5-DIHYDROFURAN-3-CARBOXYLIC ACID ETHYL ESTER, SHOWING ANTIFUNGAL ACTIVITY 2018
  • Ivanov Dmitrij Vladimirovich
  • Makhmudov Ramiz Ragibovich
  • Igidov Nazim Musabekovich
  • Novikova Valentina Vasilevna
RU2654207C1
2-AMINO-1-ARYL-5-(3,3-DIMETHYL-2-OXOBUTYLIDENE)-4-OXO-N-(THIAZOL-5-YL)-4,5-DIHYDRO-1H-PYRROLE-3-CARBOXAMIDES, EXHIBITING ANTITUMOUR AND ANTIRADICAL ACTIVITY, SYNTHESIS METHOD THEREOF AND PHARMACEUTICAL COMPOSITION BASED THEREON 2015
  • Zykova Svetlana Sergeevna
  • Bojchuk Sergej Vasilevich
  • Igidov Nazim Musabekovich
  • Odegova Tatjana Fedorovna
  • Zakhmatov Anton Viktorovich
  • Galembikova Ajgul Rafikovna
  • Ramazanov Bulat Rashitovich
RU2605091C2
N-SUBSTITUTED AMIDES OF 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL) 2-BUTENOIC ACID, EXHIBITING ANTIMICROBIAL ACTIVITY 2009
  • Mel'Nikova Natal'Ja Aleksandrovna
  • Odegova Tat'Jana Fedorovna
  • Borodin Anton Jur'Evich
  • Igidov Nazim Musabekovich
  • Chashchina Svetlana Viktorovna
  • Borodina Tat'Jana Viktorovna
  • Kirillova Rimma Valentinovna
RU2429225C2
2-{[2-(ADAMANTAN-1-YL)-2-OXOETHYLIDENEHYDRAZINYL-4-(Β-NAPHTHALYL)-4-OXOBUT-2-ENOYL]THIO} SODIUM ETHANOATE WITH WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITY 2023
  • Pulina Natalia Alekseevna
  • Kuznetsov Aleksandr Sergeevich
  • Chashchina Svetlana Viktorovna
RU2808431C1
ANTI-TUBERCULOSIS DRUG BASED ON (Z)-3-(3,3-DIMETHYL-2-OXOBUTYLIDENE) -3,4-DIHYDRO-2H-1,4-BENZOXAZIN-2-ONE AND A METHOD FOR ITS SYNTHESIS 2020
  • Maslivets Andrej Nikolaevich
  • Mashevskaya Irina Vladimirovna
  • Balandina Svetlana Yurevna
  • Stepanova Ekaterina Evgenevna
  • Dmitriev Maksim Viktorovich
  • Kovalenko Ilya Ivanovich
  • Drobkova Vera Anatolevna
  • Remezovskaya Natalya Borisovna
RU2748748C1

RU 2 768 761 C1

Authors

Syutkina Alena Ivanovna

Makhmudov Ramiz Ragibovich

Shipilovskikh Sergej Aleksandrovich

Dates

2022-03-24Published

2021-07-19Filed