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2 770 598

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IPC

A61K31/381(2006-01-01)

A61P31/10(2006-01-01)

C07D333/66(2006-01-01)

(21) (22)

Application

2021119246, 2021-06-29

(24)

Start date

2021-06-29

(22)

Actual filing date

2021-06-29

(45)

Published

2022-04-18

(72)

Inventor

Shipilovskikh Sergej AleksandrovichRubtsov Aleksandr EvgenevichMakhmudov Ramiz RagibovichShipilovskikh Darya AleksandrovnaTkachenko Aleksandr GeorgievichNesterova Larisa Yurevna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Natsionalnyj Issledovatelskij Universitet"

APPLICATION OF ANTIFUNGAL AGENT BASED ON 2-((4-R1-5-R2-3-(ETHOXYCARBONYL)THIOPHENE-2-IL)AMINO)-4-OXO-4-R3-BUT-2-ENO ACIDS IN RELATION TO CANDIDA ALDICANS Russian patent published in 2022 - IPC A61K31/381 A61P31/10 C07D333/66

Abstract RU 2770598 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to the use of 2-((4-R¹-5-R²-3-(ethoxycarbonyl)thiophene-2-yl)amino)-4-oxo-4-R3-but-2-eno acids 1a,b as an antimicrobial agent against Candida aldicans.

EFFECT: compounds with high yields have been obtained, having pronounced antifungal activity against Candida aldicans, as well as low toxicity.

1 cl, 4 ex

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RU 2 770 598 C1

Authors

Shipilovskikh Sergej Aleksandrovich

Rubtsov Aleksandr Evgenevich

Makhmudov Ramiz Ragibovich

Shipilovskikh Darya Aleksandrovna

Tkachenko Aleksandr Georgievich

Nesterova Larisa Yurevna

Dates

2022-04-18—Published

2021-06-29—Filed