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(19)

(11)

2 768 865

(13)

(51)

IPC

C07D271/07(2006-01-01)

C07D285/08(2006-01-01)

C07D413/06(2006-01-01)

C07D417/06(2006-01-01)

A61K31/4245(2006-01-01)

A61K31/433(2006-01-01)

A61P1/00(2006-01-01)

A61P11/00(2006-01-01)

A61P13/00(2006-01-01)

A61P25/00(2006-01-01)

A61P27/02(2006-01-01)

A61P29/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2019134453, 2018-05-02

(24)

Start date

2018-05-02

(22)

Actual filing date

2018-05-02

(45)

Published

2022-03-25

(72)

Inventor

Pevarello PaoloSodano MariangelaSeveri EldaVitalone RoccoThomas RussellCusano Valentina

(73)

Holder

Axxam S.P.A.

HETEROCYCLIC ANTAGONISTS P2X7 Russian patent published in 2022 - IPC C07D271/07 C07D285/08 C07D413/06 C07D417/06 A61K31/4245 A61K31/433 A61P1/00 A61P11/00 A61P13/00 A61P25/00 A61P27/02 A61P29/00 A61P35/00

Abstract RU 2768865 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to compounds of formula (I)

or pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and to methods of producing said compounds.

EFFECT: novel compounds which can be used in treating conditions or diseases mediated by the P2X7 receptor are obtained.

15 cl, 1 dwg, 2 tbl, 251 ex

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RU 2 768 865 C2

Authors

Pevarello Paolo

Sodano Mariangela

Severi Elda

Vitalone Rocco

Thomas Russell

Cusano Valentina

Dates

2022-03-25—Published

2018-05-02—Filed