METHODS FOR TREATING MULTIPLE SCLEROSIS USING AUTOLOGOUS T CELLS Russian patent published in 2022 - IPC A61K35/14 A61P25/00 

Abstract RU 2769474 C2

FIELD: medicine.

SUBSTANCE: present invention relates to biotechnology and medicine, in particular, to methods for treating or preventing multiple sclerosis (MS) in a patient, as well as applications of autologous cytotoxic T cells (CTLs) for producing a medicinal product for treating or preventing multiple sclerosis. Described methods and applications relate to the use of autologous CTLs expressing a T cell receptor specifically binding to the EBV peptide presented on class I MHC, wherein at least 7% of the CTLs express IFNγ.

EFFECT: invention provides a possibility of expanding the range of products for treating such an autoimmune disease as multiple sclerosis.

34 cl, 2 tbl, 2 ex, 3 dwg

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RU 2 769 474 C2

Authors

Khanna, Rajiv

Smith, Corey

Aftab, Blake, Tolu

Dates

2022-04-01Published

2018-01-19Filed