FIELD: biotechnology.
SUBSTANCE: described is an antibody-drug conjugate (ADC) for delivering a drug to human SEZ6-expressing cells, wherein the conjugate has the structure:
,
wherein the antibody (Ab) contains an anti-SEZ6 antibody with the heavy chain sequence SEQ ID NO: 3 and the light chain sequence SEQ ID NO: 4, and wherein n equals 2.
EFFECT: invention expands the range of means for delivering a drug to human SEZ6-expressing cells.
1 cl, 9 dwg, 6 tbl, 10 ex
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Authors
Dates
2022-04-18—Published
2019-05-30—Filed