ANALGESIC COMPOUNDS AND METHODS FOR APPLICATION THEREOF Russian patent published in 2022 - IPC C07C62/32 C07C67/56 C07C67/297 C07C69/757 A61K31/194 A61K31/225 A61P25/00 A61P29/00 

Abstract RU 2772045 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound by the general formula (I), exhibiting an analgesic or anti-inflammatory effect. In the formula (I), both R are the same and constitute an ethyl group or a residue of an ester of (L)-malic acid. The invention also relates to an application of compounds by the general formula (I), wherein both R are the same and constitute hydrogen, an ethyl group, or a residue of an ester of (L)-malic acid, as an analgesic or anti-inflammatory agent, as inhibitors of ASIC1a and ASIC3 ion channels, or as a medicinal product for preventing or treating pain and inflammation. (I).

EFFECT: creation of a compound with an analgesic or anti-inflammatory effect.

7 cl, 15 dwg, 19 ex

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RU 2 772 045 C2

Authors

Kublitskii Vadim Sergeevich

Belozerova Olga Aleksandrovna

Iatskin Oleg Nikolaevich

Osmakov Dmitrii Igorevich

Koshelev Sergei Gennadevich

Andreev Iaroslav Alekseevich

Diachenko Igor Aleksandrovich

Palikov Viktor Anatolevich

Palikova Iuliia Aleksandrovna

Kozlov Sergei Aleksandrovich

Dates

2022-05-16Published

2020-10-22Filed