COMPOSITION FOR EFFECTIVE LIPID DELIVERY TO HUMAN TEAR FILM USING SALT-SENSITIVE EMULSION SYSTEM Russian patent published in 2022 - IPC A61K9/107 A61K31/47 A61K31/7028 A61K31/717 A61K47/44 A61P27/04 

Abstract RU 2772357 C2

FIELD: medicine; pharmaceutics.

SUBSTANCE: first invention of a group is an artificial tear emulsion, which is a submicron emulsion, wherein the emulsion has the following composition: 0.5 % wt./wt. of polysorbate 80; 0.5 % wt./wt. of sodium carboxymethylcellulose; 1.0 % wt./wt. of glycerin; 0.6 % wt./wt. of boric acid; 0.1 % wt./wt. of Pemulen, which is carbomer-copolymer of type A; 0.25 % wt./wt. of castor oil; 0.25 % wt./wt. of erythritol; 0.25 % wt./wt. of levocarnitine; sodium hydroxide for bringing pH to 7.3; water, and optionally 0.01 % wt./wt. of Purite, which is stabilized oxychlorocomplex. The emulsion does not preferably contain a preservative. The second invention of the group is a method for the treatment of a “dry eye” syndrome, including the administration of the specified emulsion.

EFFECT: group of inventions provides for prolongation of time of tear film breaking, increase in the efficiency relatively to the treatment of a “dry eye” syndrome, and reduction in the rate of side effects.

3 cl, 1 tbl, 1 ex

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RU 2 772 357 C2

Authors

Vehige Joseph G.

Simmons Peter A.

Dates

2022-05-19Published

2012-12-07Filed