METHOD FOR DEVELOPING TREATMENT TACTICS FOR ACUTE ARTERIAL THROMBOSES ASSOCIATED WITH COVID-19 Russian patent published in 2022 - IPC A61M25/01 A61K38/49 A61P7/02 

Abstract RU 2773295 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to the treatment of acute thrombotic conditions of the main arteries, and can be used in the treatment of COVID-19-associated thrombosis in an inpatient setting. As indications for choosing a method for treatment, the presence or absence of a cytokine storm, the level of D-dimer, the degree of acute arterial ischemia, and the level of blood oxygen saturation are determined. In the absence of a cytokine storm, the level of D-dimer is from 1000 ng/ml and above, the degree of acute arterial ischemia is not higher than 2B, the degree of blood oxygen saturation is at least 90%, and within 3 days from the onset of the disease, transarterial controlled selective catheter thrombolysis is performed with introduction of an alteplase thrombus into the body. With indicators of acute arterial ischemia of 2-3 degrees, the level of D-dimer is above 1000 ng/ml, the degree of blood oxygen saturation is less than 90%, or requiring high-flow oxygenation, and in the presence of cytokine storm phenomena, systemic transvenous thrombolysis is performed with alteplase.

EFFECT: method allows to develop an algorithm for the treatment of acute thrombosis of the main arteries associated with COVID-19.

1 cl, 3 ex

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Authors

Nikolskij Aleksandr Viktorovich

Volkov Dmitrij Vladimirovich

Fedorovtsev Vladimir Andreevich

Kosonogov Aleksej Yakovlevich

Mukhin Aleksej Stanislavovich

Rybinskij Aleksej Dmitrievich

Trofimov Nikolaj Aleksandrovich

Sharabrin Evgenij Georgievich

Dates

2022-06-01Published

2021-11-12Filed