FIELD: medical equipment.
SUBSTANCE: group of inventions relates to medicine, namely, to a medical apparatus for irreversible electroporation and to a method for treatment using irreversible electroporation. Apparatus comprises a probe, an electrical signal generator, and a controller. The probe comprises an insertable tube and a distal node. The tube is configured to be inserted into a body cavity of the patient. The node is distally connected with the insertable tube and comprises electrodes. The electrodes are configured to be brought into contact with tissue inside the body cavity. The electrical signal generator is configured to supply biphase electrical pulses simultaneously to a group of two or more electrodes with energy sufficient to conduct irreversible electroporation of the tissue in contact with the electrodes of the group. When implementing the method, a probe is provided to be inserted into the body cavity of the patient. Biphase electrical pulses are supplied simultaneously to a group of two or more electrodes with energy. The time-varying voltage differences between the electrodes of the group are measured using the controller, and the biphase electrical pulses supplied to the electrodes of the group are adjusted so that the voltage differences do not exceed a preset threshold value while the biphase electrical pulses are supplied. The adjustment of the phase of the biphase electrical pulses therein involves compensating the phase shift between the corresponding voltage signals measured on pairs of electrodes of the group, and the amplitude of biphase electrical pulses is adjusted so as to compensate for differences in the corresponding peak voltages measured on pairs of electrodes of the group. Due to the specifics of adjusting the electrical impulses, the grouping of adjacent electrodes is ensured such as to create a section of effective electroporation with a larger area than one electrode.
EFFECT: ensured treatment using irreversible electropolation.
10 cl, 6 dwg, 1 tbl
