BACTERIAL LUX-BIOSENSOR WITH INCREASED SENSITIVITY FOR DETECTION OF ACYL HOMOSERINE LACTONE DERIVATIVES Russian patent published in 2022 - IPC G01N33/569 G01N21/76 C12N15/63 C12N1/21 C12Q1/02 

Abstract RU 2777196 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to bacterial lux-biosensors for the detection of sub-nanomolar concentrations of acyl homoserine lactone derivatives, as well as to bacterial lux-biosensors for the detection of acyl homoserine lactone derivatives. Biosensors consist of Escherichia coli cells transformed with a pair of plasmids, which contain genes obtained either from Aliivibrio fischeri, or from Aliivibrio logei, or from Aliivibrio salmonicida, and luxCDABE Photorhabdus luminescens genes.

EFFECT: obtaining bacterial lux-biosensors for the detection of homoserine lactone derivatives.

6 cl, 5 dwg, 1 ex

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RU 2 777 196 C2

Authors

Bazhenov Sergej Vladimirovich

Kessenikh Andrej Grigorevich

Novoyatlova Ulyana Sergeevna

Shcheglova Ekaterina Sergeevna

Fomin Vadim Valerevich

Khrulnova Svetlana Alekseevna

Zavilgelskij Gennadij Borisovich

Kuznetsova Svetlana Borisovna

Manukhov Ilya Vladimirovich

Dates

2022-08-01Published

2020-12-30Filed