FIELD: pharmaceuticals.
SUBSTANCE: invention relates to an application of a JNK (c-Jun N-terminal kinase) inhibitor sodium 11H-indeno[1,2-b]quinoxaline-11-onoxime as a venlafaxine metabolism inducer, which can be used to personalise and increase the effectiveness of antidepressant therapy, in particular, to increase the level of intensity of drug transformation in weak venlafaxine metabolisers (persons with a low expression of CYP2D6 or patients with liver diseases) up to the normal level.
EFFECT: effective induction (stimulation) of venlafaxine metabolism.
1 cl, 1 tbl, 1 ex
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Authors
Dates
2022-08-03—Published
2021-06-28—Filed