VENLAFAXINE METABOLISM INDUCER Russian patent published in 2022 - IPC A61K31/498 A61P25/24 A61P43/00 

Abstract RU 2777409 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to an application of a JNK (c-Jun N-terminal kinase) inhibitor sodium 11H-indeno[1,2-b]quinoxaline-11-onoxime as a venlafaxine metabolism inducer, which can be used to personalise and increase the effectiveness of antidepressant therapy, in particular, to increase the level of intensity of drug transformation in weak venlafaxine metabolisers (persons with a low expression of CYP2D6 or patients with liver diseases) up to the normal level.

EFFECT: effective induction (stimulation) of venlafaxine metabolism.

1 cl, 1 tbl, 1 ex

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RU 2 777 409 C1

Authors

Zyuzkov Gleb Nikolaevich

Udut Vladimir Vasilevich

Bryushinina Olga Sergeevna

Abdrashitova Natalya Yurevna

Zyuzkova Yuliya Gennadevna

Yanovskaya Elena Anatolevna

Frelikh Galina Andreevna

Lakeev Aleksandr Pavlovich

Dates

2022-08-03Published

2021-06-28Filed