FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, in particular, to new compositions of nucleic acid molecules encoding the modified consensus antigen MUC16, and can be used in medicine. Disclosed is a new modified consensus antigen MUC16, and a possibility of application thereof as a tumour marker is demonstrated.
EFFECT: production of safe and effective combined vaccines applicable against MUC16-expressing tumours thereby providing treatment and contributing to the survival of subjects affected by such types of cancer.
31 cl, 30 dwg, 28 tbl, 6 ex
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