FIELD: medicine.
SUBSTANCE: group of inventions relates to a strain Lactobacillus mucosae and its use. A strain Lactobacillus mucosae NK41 KCCM12091P is proposed, suppressing the expression of protein p16 as an aging factor. The effective amount of the specified strain, its thermally inactivated probiotic, or its culture is used in a pharmaceutical composition for use for the prevention or treatment of memory disorder and learning disability, or a pharmaceutical composition for use in the treatment or prevention of a mental disorder, or a pharmaceutical composition for use for the prevention or treatment of an inflammatory disease. A food composition containing the specified strain, its thermally inactivated probiotic, or its culture is also proposed. The use of compositions containing the specified strain, its thermally inactivated probiotic, or its culture is also proposed for the administration to a patient for the prevention, relief, or treatment of a memory disorder and learning disability, or for prevention, relief, or treatment of a mental disorder, or for prevention, relief, or treatment of an inflammatory disease.
EFFECT: invention provide memory recovery, reduce disturbing behavior, have an effect of inhibition of an inflammatory response.
16 cl, 8 tbl, 6 ex, 12 dwg
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Authors
Dates
2022-08-24—Published
2018-11-20—Filed