THE COMPOSITION OF FENFLURAMINE, COMPATIBLE WITH A KETOGENIC DIET Russian patent published in 2022 - IPC A61K9/08 A61K31/19 A61K31/4184 A61P25/08 

Abstract RU 2778848 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to the field of medicine, namely neurology, and is intended for use in the treatment of epileptic encephalopathy. The composition for increasing compliance with the ketogenic diet by a patient diagnosed with refractory epilepsy contains fenfluramine hydrochloride, sodium methylparaben, sodium ethylparaben, sucralose, hydroxyethyl cellulose, flavor, potassium citrate monohydrate, citric acid monohydrate and water. The components are used in the stated quantities. A method for increasing compliance with the ketogenic diet is also presented, including administration to the patient, over a period of several days, of the specified composition. In other embodiments, methods for treating a patient with a diagnosis of epileptic encephalopathy are presented.

EFFECT: use of the group of inventions makes it possible to increase the effectiveness of the treatment of epileptic encephalopathy and/or seizures experienced by patients with Dravet syndrome, Lennox-Gastaut syndrome or Doose syndrome who are on a ketogenic diet.

42 cl, 12 tbl, 3 ex

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RU 2 778 848 C2

Authors

Abu-Izza, Khawla

Hickman, David

Morrison, Glenn

Boyd, Brooks M.

Dates

2022-08-26Published

2018-09-25Filed