FIELD: biochemistry.
SUBSTANCE: invention relates to the field of biochemistry, in particular to an antibody or its antigen-binding fragment, which specifically bind to CTLA4, its production method, as well as to a composition and a conjugate containing it. Nucleic acid encoding the above-mentioned antibody or its fragment is also presented, as well as a vector and a cell containing it. The invention also relates to the use of the above-mentioned antibody or its fragment for the production of a bispecific antibody.
EFFECT: invention is effective for the treatment of a malignant neoplasm.
60 cl, 27 dwg, 6 tbl, 9 ex
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