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2 780 405

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IPC

C07D241/24(2006-01-01)

A61K31/4965(2006-01-01)

(21) (22)

Application

2020138845, 2020-11-26

(24)

Start date

2020-11-26

(22)

Actual filing date

2020-11-26

(45)

Published

2022-09-22

(72)

Inventor

Demidov Evgenii IgorevichIgnatenko Oleg AleksandrovichNilov Denis IgorevichSemenov Aleksandr SergeevichSemenova Inna AleksandrovnaShchipalkin Andrei Aleksandrovich

(73)

Holder

Aktsionernoe Obshchestvo Komponent"

CRYSTAL AMMONIUM SALT OF 3-HYDROXY-6-FLUOROPYRAZINE-2-CARBONITRILE - SEMI-PRODUCT IN SYNTHESIS OF 3-HYDROXY-6-FLUOROPYRAZINE-2-CARBOXAMIDE Russian patent published in 2022 - IPC C07D241/24 A61K31/4965

Abstract RU 2780405 C2

FIELD: chemistry.

SUBSTANCE: invention relates to ammonium salt of 3-hydroxy-6-fluoropyrazine-2-carbonitrile, its production method, and method for the production of favipiravir from ammonium salt of 3-hydroxy-6-fluoropyrazine-2-carbonitrile.

EFFECT: new technological method for synthesis of favipiravir from ammonium salt of 3-hydroxy-6-fluoropyrazine-2-carbonitrile is developed, which is easy to implement on an industrial scale and does not require special complex equipment; implementation of the method, according to the invention, allows for significant reduction in the content of impurities in a target product, as well as avoidance of the formation of toxic production waste.

3 cl, 3 ex, 8 dwg

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RU 2 780 405 C2

Authors

Demidov Evgenii Igorevich

Ignatenko Oleg Aleksandrovich

Nilov Denis Igorevich

Semenov Aleksandr Sergeevich

Semenova Inna Aleksandrovna

Shchipalkin Andrei Aleksandrovich

Dates

2022-09-22—Published

2020-11-26—Filed