MEANS FOR BLOCKING THE EFFECTS OF LIPOTEICHOIC ACIDS - TOLL-LIKE RECEPTOR 2 AGONISTS Russian patent published in 2022 - IPC A61K31/739 C12P19/00 C12N1/20 

Abstract RU 2781012 C1

FIELD: biotechnology, pharmacology and medicine.

SUBSTANCE: invention relates to biotechnology, pharmacology and medicine. The use of lipopolysaccharide produced by a strain of phototrophic bacterium Rhodobacter capsulatus PG RNCIM IBFM RAS V-2381D as a non-toxic blocking factor protecting against the effects of lipoteichoic acids, Toll-like receptor 2 agonists.

EFFECT: invention provides for expanding the range of drugs based on non-toxic lipopolysaccharide produced by a strain of phototrophic bacterium Rhodobacter capsulatus PG for blocking the activation of intracellular signaling pathways by TLR2 ligands and the synthesis of pro-inflammatory cytokines by immune cells.

1 cl, 6 dwg

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RU 2 781 012 C1

Authors

Zubova Svetlana Vladimirovna

Prokhorenko Izabella Ruvimovna

Grachev Sergej Vitalevich

Dates

2022-10-04Published

2022-04-19Filed