FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to otolaryngology, and deals with immunotherapy of purulent rhinosinusitis. Method is based on data of genotyping by signs of allele polymorphism of cytokine gene, obtained in analysis of blood cells and cells isolated from washings from sinuses. If high-producing allele of gene LL-β "2/2" and low-producing allele of gene TL-1RA "1/1" are identified in patient, immunotherapy with preparation of recombinant 1L-1RA, conditioned by regulation of activation of phagocytic activity of neutrophils, is performed.
EFFECT: method ensures efficient treatment of patients with lingering course of disease, who cannot be treated by traditional methods of therapy, due to individual selection of immunopreparation taking into account immunogenetic peculiarities of organism.
6 dwg, 4 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTION OF CLINICAL EFFECTIVENESS IN CHRONIC PURULENT RHINOSINUSITIS | 2008 |
|
RU2379050C2 |
METHOD OF IMMUNOTHERAPY OF PURULENT RHINOSINUSITIS | 2009 |
|
RU2408385C1 |
METHOD FOR PROGNOSIS OF TREATMENT EFFECTIVENESS WITH RECOMBINANT CYTOKINE REGULATING INFLAMMATION | 2004 |
|
RU2271827C1 |
METHOD OF TREATING CHRONIC RHINOSINUSITIS | 2011 |
|
RU2469737C1 |
METHOD FOR PREDICTING THE EFFICIENCY OF THERAPY WITH INTERLEUKIN-1 | 2005 |
|
RU2301012C2 |
DIAGNOSTIC TECHNIQUE FOR PARKINSON DISEASE IN PATIENTS WITH OLFACTORY DYSFUNCTION | 2011 |
|
RU2478209C1 |
METHOD FOR IMMUNOTHERAPY OF PURULENT RHINOSINUSITIS WITH CONCOMITANT TYPE 2 DIABETES MELLITUS | 2020 |
|
RU2763672C1 |
METHOD FOR PREDICTING DEVELOPMENT OF OTITIS MEDIA IN PATIENTS WITH RHINOSINUSITIS | 2020 |
|
RU2750024C1 |
METHOD OF PATIENT REHABILITATION AFTER TYMPANOPLASTY | 2007 |
|
RU2355416C2 |
SOLUTIONS AND METHODS FOR INHIBITING PAIN, CARTILAGE INFLAMMATION AND DESTRUCTION | 2000 |
|
RU2271825C2 |
Authors
Dates
2012-08-10—Published
2010-06-30—Filed