METHOD OF IMMUNOTHERAPY OF PURULENT RHINOSINUSITIS Russian patent published in 2012 - IPC A61B10/00 G01N33/48 A61K38/20 A61P11/02 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to otolaryngology, and deals with immunotherapy of purulent rhinosinusitis. Method is based on data of genotyping by signs of allele polymorphism of cytokine gene, obtained in analysis of blood cells and cells isolated from washings from sinuses. If high-producing allele of gene LL-β "2/2" and low-producing allele of gene TL-1RA "1/1" are identified in patient, immunotherapy with preparation of recombinant 1L-1RA, conditioned by regulation of activation of phagocytic activity of neutrophils, is performed.

EFFECT: method ensures efficient treatment of patients with lingering course of disease, who cannot be treated by traditional methods of therapy, due to individual selection of immunopreparation taking into account immunogenetic peculiarities of organism.

6 dwg, 4 ex