SYNBIOTIC COMPOSITION FOR SUPPRESSING MICROBIAL PATHOGENS OF INTESTINAL INFECTIONS AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2022 - IPC A61K31/733 A61K35/745 A61K36/28 A61P1/00 

FIELD: biotechnology.

SUBSTANCE: group of inventions relates to biotechnology, the pharmaceutical and food industries, and pertains to a synbiotic composition for suppressing pathogens of intestinal infections based on bifidobacteria and a fraction of burdock root fructans, as well as to a method for production thereof. Content of components in 1 g of the composition: lyophilised biomass of bifidobacteria 10⁸ to 10¹⁰ colony-forming units; fraction of burdock root fructans 0.80 to 0.98 g. A fraction of burdock root fructans is herein used, produced by crushing burdock roots, performing water extraction at a temperature of 60 to 90°C for 30 min, separating the extract from the solid residue by filtration, removing the high molecular weight impurities by ultrafiltration, removing the low molecular weight impurities by sorption on activated carbon, concentrating the extract by vacuum evaporation, adding ethanol to the extract as calculated for the final content thereof at 20 vol.%, holding in cold, separating and drying the resulting deposited fraction of fructans. The composition can be made in the form of a powder or capsules. Method for producing the composition consists in producing a fraction of burdock root fructans by the above method, mixing said fraction with lyophilised biomass of bifidobacteria, packing in packets or encapsulating.

EFFECT: possibility of producing a synbiotic composition containing a fraction of burdock root fructans, with a greatest stimulating effect on the growth of bifidobacteria, ensuring the maximum level of suppression of pathogens of intestinal infections thereby.

3 cl, 3 tbl, 3 ex