THERAPEUTIC COMPOSITION FOR THE TREATMENT OF OTITIS MEDIA WITH PERFORATION OF THE TYMPANIC MEMBRANE Russian patent published in 2022 - IPC A61K31/14 A61K31/192 A61K31/496 A61K47/32 A61K47/36 A61K9/08 A61P27/16 

Abstract RU 2782926 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to the field of pharmacology and concerns a therapeutic composition in the form of drops for the treatment of otitis media with perforation of the tympanic membrane, which can be used to restore the integrity of the tympanic membrane, and as a result, human hearing. The composition includes ciprofloxacin, a chemotherapeutic antiseptic agent - miramistin (benzyldimethyl-myristoylamino-propylammonium chloride monohydrate) and a non-steroidal anti-inflammatory agent - ketoprofen, as a thickener - carbomer and as a solubilizer and viscosity stabilizer - sodium hyaluronate in the following ratio: ciprofloxacin 0.5 g; benzyldimethyl-myristoylamino-propylammonium chloride monohydrate - 0.01 g; ketoprofen lysine salt - 0.5 g; carbomer in concentration - 0.05 g; sodium hyaluronate at a concentration of 0.1 g; water - 100 ml.

EFFECT: composition provides a combined therapeutic effect: the removal of inflammation and the suppression of pathogenic microorganisms, the reduction of the index of resistance to pathogenic microorganisms that cause otitis media with damage to the eardrum, and the prolongation of the therapeutic effect.

1 cl, 3 tbl, 3 ex

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RU 2 782 926 C1

Authors

Martseva Diana Sergeevna

Zhilyakova Elena Teodorovna

Dates

2022-11-07Published

2022-03-29Filed