VACCINE AGAINST FELINE LEUKEMIA VIRUS Russian patent published in 2022 - IPC A61K39/12 C12N7/00 

FIELD: veterinary medicine.

SUBSTANCE: vaccine for contribution to prevention of a disease caused by FeLV is proposed, containing an immunogenic composition containing a particle of RNA-replicon of an alpha-virus, which encodes an antigen of a feline leukemia virus (hereinafter – FeLV). A method for immunization of a feline against a pathogenic FeLV is proposed, including administration to the feline of immunologically effective amount of the vaccine.

EFFECT: vaccine protects vaccinated animals from a debilitating unhealthy condition caused by FeLV infection as effectively as its inactivated analogue does; vaccine based on the whole virus protected 100% of cats, when administered in a mode with two doses, i.e., prime and buster vaccination; vaccine RP-FeLV protected 87% of cats, when administered in the form of a single dose; on the contrary, a commercially available vaccine protected only 57% of cats, even in the mode with two doses.

15 cl, 4 tbl, 3 ex