FIELD: vaccines.
SUBSTANCE: vaccine is provided to help prevent disease caused by feline calicivirus (FCV). The vaccine contains a Venezuelan equine encephalomyelitis (VEE) alpha virus RNA replicon RNA particle that encodes an FCV antigen representing a capsid protein and a pharmaceutically acceptable carrier. The vaccine may be used to immunize a feline subject against pathogenic FCV. A method for immunizing a feline against pathogenic FCV is proposed, which includes administering an immunologically effective amount of the proposed vaccine to the feline.
EFFECT: vaccine stimulates the production of more widely reactive virus-neutralizing (VN) antibodies and therefore provides better protection against new field isolates.
25 cl, 8 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| POLYVALENT VACCINE FOR CATS | 2018 |
|
RU2797538C2 |
| VACCINE AGAINST FELINE LEUKEMIA VIRUS | 2018 |
|
RU2784533C2 |
| VACCINE AGAINST RABIES VIRUS | 2018 |
|
RU2782350C2 |
| VACCINE TO SWINE INFLUENZA A VIRUS | 2018 |
|
RU2787596C2 |
| ALPHAVIRUS REPLICON PARTICLE | 2018 |
|
RU2795596C2 |
| FMDV RECOMBINANT VACCINES AND USE THEREOF | 2015 |
|
RU2745373C2 |
| VACCINES BASED ON VIRUS-LIKE PARTICLES (VLP) OF CANINE PARVOVIRUS (CPV) AND APPLICATION THEREOF | 2016 |
|
RU2710854C1 |
| RABIES VACCINE | 2014 |
|
RU2712743C2 |
| FMDV-E2 FUSION PROTEINS AND USE THEREOF | 2016 |
|
RU2714428C2 |
| LIPOSOMAL ADJUVANT COMPOSITIONS | 2016 |
|
RU2736642C2 |
