FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to oncology, and can be used to predict early relapses of uterine body clear cell carcinoma. The relative expression of CDKN2A, L1CAM, ERBB2, and UBE2C genes in tumor tissue relative to normal endometrial tissue is determined by real-time PCR. If the relative expression value of the CDKN2A gene is equal to or higher than 7.6, L1CAM is equal to or higher than 5.4, the ERBB2 gene is equal to or higher than 3.9, and the UBE2C gene is equal to or higher than 3.7, the appearance of a relapse of the disease is predicted in the first two years after surgery, regardless of the stage of the disease.
EFFECT: method allows predicting early relapses of uterine body clear cell carcinoma in the first two years after surgery by determining the relative expression of CDKN2A, L1CAM, ERBB2 and UBE2C genes in the tumor tissue.
1 cl, 2 ex
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