FIELD: biotechnology.
SUBSTANCE: group of inventions is described, including a ligand-drug against B7H3 conjugate or its pharmaceutically acceptable salt, a pharmaceutical composition for the treatment of diseases or disorders mediated with B7H3, the use of the above-mentioned ligand-drug conjugate or its pharmaceutically acceptable salt or the pharmaceutical composition in the preparation of drugs for the treatment of B7H3-mediated diseases or disorders, and the use of the above-mentioned ligand-drug conjugate or its pharmaceutically acceptable salt or the pharmaceutical composition in the preparation of drugs for the treatment and/or prevention of cancer mediated with B7H3.
EFFECT: invention expands the arsenal of remedies against B7H3.
17 cl, 13 dwg, 9 tbl, 24 ex
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