PROCESS FOR THE PREPARATION OF 5-AMINO-N-METHYL-3,4-DICYANOPYRAZOLE Russian patent published in 2022 - IPC C07D231/38 

Abstract RU 2785675 C1

FIELD: organic and pharmaceutical chemistry.

SUBSTANCE: invention relates to organic and pharmaceutical chemistry, and in particular to a method for producing 5-amino-N-methyl-3,4-dicyanopyrazole, which includes the interaction of tetracyanoethylene with hydrazine in methanol at room temperature for 20-25 minutes, while as hydrazine uses spent rocket fuel based on unsymmetrical dimethylhydrazine.

EFFECT: developing a method for obtaining 5-amino-N-methyl-3,4-dicyanopyrazole, which can be used in the synthesis of drugs used in the treatment of oncological and neurodegenerative diseases, characterized by ease of synthesis, carrying out the reaction under standard conditions, obtaining the target product with high output, processing of fuel that has become unusable in the rocket industry.

1 cl,1 ex

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RU 2 785 675 C1

Authors

Nasakin Oleg Evgenevich

Eremkin Aleksej Vladimirovich

Lyalin German Semenovich

Ivanova Elizaveta Sergeevna

Andreeva Vera Vladimirovna

Maryasov Maksim Andreevich

Lodochnikova Olga Aleksandrovna

Dates

2022-12-12Published

2022-03-10Filed