PROCESS FOR THE PREPARATION OF 5-AMINO-3-CYANOMETHYL-1H-PYRAZOLE-4-CARBONITRILE Russian patent published in 2023 - IPC C07D231/14 

Abstract RU 2803146 C1

FIELD: chemical industry.

SUBSTANCE: invention relates to a method for obtaining 5-amino-3-cyanomethyl-1H-pyrazole-4-carbonitrile of formula 1, which is an intermediate product in the synthesis of biologically active compounds and a reagent for the synthesis of polynitrogen-containing heterocyclic compounds. The method for preparing 5-amino-3-cyanomethyl-1H-pyrazole-4-carbonitrile is characterized in that the potassium salt of the malononitrile dimer is reacted with hydrazinium sulphate in water by heating 90°C with stirring for 2 hours.

EFFECT: reduced number of synthesis stages and increased yield of the target product based on the initial malononitrile.

1 cl, 1 tbl, 1 ex

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RU 2 803 146 C1

Authors

Stepanova Sofiia Fedorovna

Dotsenko Viktor Viktorovich

Semenova Aminat Manafovna

Dates

2023-09-07Published

2023-02-13Filed