FIELD: medicine; oncology.
SUBSTANCE: invention relates to the field of medicine, namely to oncology; it is intended for the treatment of cancer. A method for the treatment of cancer in a subject who needs such a treatment includes administration to the specified subject of effective amount of a conjugate of a topoisomerase I SN-38 inhibitor, connected to a macromolecule via a linker, in a combination with effective amount of poly-ADF ribose-polymerase (PARP inhibitor).
EFFECT: use of the invention provides improved results of the treatment of cancer in a subject.
9 cl, 4 dwg, 2 ex
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