FIELD: medicine; ophthalmology.
SUBSTANCE: invention relates to medicine, namely to ophthalmology; it can be used for restoration or improvement of a visual function in an individual with retinal degeneration. The method includes administration to the individual of at least one recombinant expression vector containing one or several of: i) a nucleotide sequence encoding MW-opsin; ii) a nucleotide sequence encoding LW-opsin; and iii) a nucleotide sequence encoding SW-opsin, where the specified nucleotide sequence is functionally connected to a promotor other than an opsin promotor, and it is expressed in a retinal cell in the individual, which is a retinal ganglion cell, an amacrine cell, a horizontal cell, or a bipolar cell.
EFFECT: method provides restoration or improvement of a visual function in an individual due to expression of the specified nucleic acid in retinal cells of this individual.
22 cl, 22 dwg, 1 ex
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