FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology. A pptA tautomerase consisting of the amino acid sequence represented by SEQ ID NO: 1, wherein arginine, which is an amino acid corresponding to position 31 in SEQ ID NO: 3, is substituted for histidine, is proposed. A polynucleotide encoding the pptA tautomerase, an Escherichia coli microorganism, which produces L-tryptophan and contains the pptA tautomerase or a polynucleotide encoding the pptA tautomerase, and a method to produce L-tryptophan, are also proposed.
EFFECT: invention makes it possible to increase the L-tryptophan yield.
5 cl, 1 tbl, 2 ex
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