FUNCTIONALIZED HYALURONIC ACID OR ITS DERIVATIVE FOR THE TREATMENT OF INFLAMMATORY CONDITIONS Russian patent published in 2023 - IPC C08B37/08 A61K31/728 A61K45/06

Abstract RU 2792001 C2

FIELD: pharmaceutics.

SUBSTANCE: group of inventions relates to functionalized hyaluronic acid. Functionalized hyaluronic acid or its derivative of formula (I) is disclosed

(I),

where R₁, R₂, R₃, R₄ independently represent the H, SO_3-, acyl group of a carboxylic acid of the aliphatic, aromatic, arylaliphatic, cycloaliphatic or heterocyclic series, -CO-(CH₂)₂-COOY, where Y is a negative charge or H, and R is Z(1) or Z(2), and R₅ is -CO-CH₃, H, SO₃-, acyl group of carboxylic acid of the aliphatic, aromatic, arylaliphatic, cycloaliphatic or heterocyclic series, the acyl group of hyaluronic acid. A method for obtaining functionalized hyaluronic acid or its derivative and a pharmaceutical composition are also disclosed.

EFFECT: group of inventions provides treatment of pathologies caused by changes in the expression of galectins.

10 cl, 4 dwg, 1 tbl, 29 ex

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RU 2 792 001 C2

Authors

Byankini, Dzhulio

Kallegaro, Lanfranko

Dates

2023-03-15—Published

2018-10-24—Filed