FIELD: organic chemistry.
SUBSTANCE: invention relates to a method for preparing bis -adducts of maleopimaric acid methyl ester imidoamine (MEMPK) with azapolycyclic spacers. The method for obtaining bis -adducts of imidoamine of maleopimaric acid methyl ester (MEMPK) with azapolycyclic spacers of general formula (1) is carried out by reacting imidoamine MEMPK with formaldehyde and tetraazapolycyclane [2,6-dimethyl-1,4,5,8-tetraazadecalin or cis -1,6,7,12-tetraazaperhydrotetracene] in CH3OH medium in the presence of 5–15 wt.% Ymmm hierarchical zeolite in the H-form, at a molar ratio of imido-amine MEMPC: formaldehyde : tetraazapolycyclane = 2 : 4 : 1. The interaction is carried out at room temperature (~20°C) temperature and atmospheric pressure for 2.5–3.5 hours.
EFFECT: obtaining bis -adducts of imido-amine MEMPC with azapolycyclic spacers of general formula (1) with a yield of 17–29%.
1 cl, 1 tbl, 6 ex
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