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2 792 884

(13)

(51)

IPC

A61K45/06(2006-01-01)

A61K31/138(2006-01-01)

A61K31/21(2006-01-01)

A61K31/4164(2006-01-01)

A61K31/165(2006-01-01)

A61P9/12(2006-01-01)

(21) (22)

Application

2021133499, 2021-11-18

(24)

Start date

2021-11-18

(22)

Actual filing date

2021-11-18

(45)

Published

2023-03-28

(72)

Inventor

Kokoz Yurij VladimirovichMaltsev Aleksandr VladimirovichMitroshin Ivan Andreevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Teoreticheskoj I Eksperimentalnoj Biofiziki Rossijskoj Akademii Nauk Ran)

PHARMACOLOGICAL COMPOSITION FOR COMPENSATION OF ARTERIAL HYPERTENSION AND ASSOCIATED PATHOLOGIES OF THE CARDIOVASCULAR SYSTEM Russian patent published in 2023 - IPC A61K45/06 A61K31/138 A61K31/21 A61K31/4164 A61K31/165 A61P9/12

Abstract RU 2792884 C1

FIELD: medicine; cardiology.

SUBSTANCE: invention is a drug composition intended for the treatment of cardiovascular diseases. This composition can be used for treatment in the complex therapy of coronary heart disease, chronic heart failure, arterial hypertension, myocardial hypertrophy, rhythm disturbances of various origins, cardioneurosis.

EFFECT: basis of the proposed composition is the sharingβ - adrenoblockers,α₂-adrenergic agonists, as well as a nitric oxide (NO) donor, which, when used together, will significantly reduce the effective therapeutic doses of each of the compounds due to a double synergistic effect (β- adrenoblocker +α_2-adrenergic agonist andα₂-blocker + NO donor), which, in turn, will lead to minimization of possible side effects associated with the intake of these compounds.

1 cl, 7 dwg

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RU 2 792 884 C1

Authors

Kokoz Yurij Vladimirovich

Maltsev Aleksandr Vladimirovich

Mitroshin Ivan Andreevich

Dates

2023-03-28—Published

2021-11-18—Filed