METHOD FOR PREDICTING THE RISK OF DEVELOPMENT OF SUBRETINAL FIBROSIS IN PATIENTS WITH EXUDATIVE FORM OF AGE-RELATED MACULAR DEGENERATION GIVEN ANTI-VEGF THERAPY Russian patent published in 2023 - IPC A61B5/00 A61F9/00 

Abstract RU 2793419 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, to ophthalmology. Optical coherence tomography is performed, determining the variability — deviation of the value of the central retinal thickness from the initial value. Additionally, fluctuation is determined as the length of the perpendicular line drawn from the retinal pigment epithelium (RPE) layer to the inner boundary membrane in the foveal zone and in the parafoveal zone; the variability and the fluctuation are determined in the course of treatment. If the value of variability is 452 mcm or more, fluctuation in the central zone of 208.5 or more, in the parafoveal zone of 285 or more, risk of subretinal fibrosis is predicted.

EFFECT: possibility of controlling the effectiveness of anti-VEGF therapy and correcting the mode of treatment depending on the values of variability and fluctuation in the foveal and parafoveal zones.

1 cl, 2 ex, 2 dwg

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RU 2 793 419 C1

Authors

Budzinskaya Mariya Viktorovna

Plyukhova Anna Anatolevna

Afanaseva Mariya Albertovna

Shelankova Aleksandra Vadimovna

Gorkavenko Filipp Vasilevich

Dates

2023-04-03Published

2022-10-03Filed