METHODS FOR TREATMENT OF INITIAL EPISODE OF TTP USING SINGLE VARIABLE DOMAINS OF IMMUNOGLOBULINS Russian patent published in 2023 - IPC C07K16/36 A61K39/395 A61P7/02 

Abstract RU 2794143 C2

FIELD: immunology; medicine.

SUBSTANCE: invention relates to a method for treating the symptoms of an initial episode of a disease associated with vWF, in particular thrombocytopenic purpura (TTP), as well as the use of a kit containing a container with a polypeptide having two single immunoglobulin variable domains (ISVD), and instructions for use, where each ISVD directed against human vWF is presented under SEQ ID NO: 19 to treat the symptoms of an initial episode of TTP.

EFFECT: invention provides an effective treatment for an initial episode of TTP that is more severe and difficult to treat than a recurrent episode.

16 cl, 5 dwg, 10 tbl, 22 ex

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RU 2 794 143 C2

Authors

Callewaert, Filip

De Winter, Hilde

Dates

2023-04-11Published

2019-02-06Filed