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2 794 763

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IPC

C07D233/64(2006-01-01)

C07D235/12(2006-01-01)

A61K31/4184(2006-01-01)

(21) (22)

Application

2022122091, 2022-08-15

(24)

Start date

2022-08-15

(22)

Actual filing date

2022-08-15

(45)

Published

2023-04-24

(72)

Inventor

Basanova Elizaveta IvanovnaNikitina Polina AndreevnaPerevalov Valerii PavlovichShishkina Larisa NikolaevnaBormotov Nikolai IvanovichSerova Olga AlekseevnaMazurkov Oleg Iurevich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Khimiko-Tekhnologicheskii Universitet Imeni D.I. MendeleevaFederalnoe Biudzhetnoe Uchrezhdenie Nauki Nauchnyi Tsentr Virusologii I Biotekhnologii Federalnoi Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelei I Blagopoluchiia Cheloveka Gnts Vb Rospotrebnadzora)

1-HYDROXY- AND 1-METHOXY-2-(4-NITROPHENYL)IMIDAZOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY AGAINST ORTHOPOXVIRUSES Russian patent published in 2023 - IPC C07D233/64 C07D235/12 A61K31/4184

Abstract RU 2794763 C1

FIELD: fine organic synthesis; medicine; virology.

SUBSTANCE: invention relates to the field of organic chemistry, specifically to new derivatives of 1-hydroxy- and 1-methoxy-2-(4-nitrophenyl)imidazole of general formula Ia-derivatives.

EFFECT: compounds of formula Ia-d R = H; R¹ = R² = CH₃ (Ia); R=H; R¹ R² = CH₂C(CH₃)₂CH₂ (Ib); R = R¹ = R² = CH₃ (Ic); R= CH₃; R¹ R² = CH₂C(CH₃)₂CH₂ (Id) have antiviral activity against orthopoxviruses.

1 cl, 2 dwg, 1 tbl, 5 ex

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RU 2 794 763 C1

Authors

Basanova Elizaveta Ivanovna

Nikitina Polina Andreevna

Perevalov Valerii Pavlovich

Shishkina Larisa Nikolaevna

Bormotov Nikolai Ivanovich

Serova Olga Alekseevna

Mazurkov Oleg Iurevich

Dates

2023-04-24—Published

2022-08-15—Filed