FIELD: organic chemistry.
SUBSTANCE: invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, where
represents
,
or
; each of X and Z is independent aryl selected from phenyl and naphthyl, H, or absent; Y represents
or
; each of L1 and L2 is independently a moiety selected from CH2, C2-10 alkyl, -((CH2)n-W)-, where n=1 and W is O or absent. The invention also relates to a pharmaceutical composition based on a compound of formula (I) and a method for inhibiting D-amino acid oxidase (DAAO) by a compound of formula (I).
EFFECT: effective inhibition of D-amino acids (DAAO) by the compound of formula (I), useful in the treatment of CNS disorders.
10 cl, 9 dwg, 1 tbl, 26 ex
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