METHOD FOR OBTAINING PLATELET RELEASATE CONTAINING GROWTH FACTORS Russian patent published in 2023 - IPC A61K35/19 A61P17/02 C12N5/00 

FIELD: pharmaceutical industry.

SUBSTANCE: method for obtaining a platelet releasate containing growth factors, the use of the obtained releasate and a composition for regenerative medicine. Method for obtaining a platelet release containing growth factors from a liquid concentrate of mammalian platelets, with the following successive steps: reduction of the content of pathogenic microorganisms in the platelet concentrate by destroying non-enveloped viruses; activation of the platelet concentrate to initiate the release of growth factors and alpha granules by platelets; isolation of fibrinogen-depleted liquid platelet release, treating the fibrinogen-depleted liquid platelet release to reduce pathogen concentration and destroy enveloped viruses; sterilizing filtration with the release of a filtered liquid containing growth factors, followed by division into portions with the same content of platelets 2×10⁵-2×20⁷ per cm³. Composition for regenerative medicine. The use of platelet releasate in regenerative medicine. Use of platelet releasate in cell culture media.

EFFECT: obtaining a therapeutic agent for enhancing the proliferation of cells of multiple lines in regenerative medicine and in the treatment of non-healing wounds and resistant ulcers, as well as in cell culture media.

20 cl, 5 ex