FIELD: chemistry.
SUBSTANCE: invention relates to use of substituted pyrrolo[3,4-b]quinolindione of general formula 1 and a pharmaceutically acceptable salt thereof, having analgesic activity, for preparing a pharmaceutical composition suitable for use as an analgesic agent. In formula 1
R1=Ph, n-MeC6H4, n-ClC6H4; R2=H, Me, Et, halogen; R3=H, Me, CH2OH; X=O, NH, NMe; Z=(CH2)n, where n=0, 1, 2, or Z=CH2OCH2.
EFFECT: disclosed is an analgesic agent.
1 cl, 2 tbl, 4 ex
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Authors
Dates
2020-01-24—Published
2018-11-22—Filed