OBTAINING ADJUVANT BASED ON ZINC ZOLEDRONATE MICRO/NANOPARTICLES AND ITS USE AS A VACCINE ADJUVANT Russian patent published in 2023 - IPC A61K39/39 A61P37/04

Abstract RU 2801598 C2

FIELD: biotechnology.

SUBSTANCE: invention can be used in medical practice. The invention discloses a vaccine adjuvant based on zinc zoledronate microparticles, which contains zinc and zoledronic acid, respectively, as well as possible additives based on phosphate and aluminum. The method of its preparation includes carrying out mixed precipitation in a soluble salt solution containing zinc ions, zoledronic acid and sodium hydroxide.

EFFECT: invention can be used as an immunostimulating additive and adjuvant in the preparation of pharmaceutical compositions and formulations.

19 cl, 9 ex, 6 tbl, 7 dwg

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RU 2 801 598 C2

Authors

Zhao, Qinjian

Huang, Xiaofen

Chen, Siyi

Li, Yike

Zhang, Cai

Xia, Ningshao

Dates

2023-08-11—Published

2020-04-10—Filed