COMPOUNDS BASED ON ISOTHIAZOLO[5,4-d]PYRIMIDINE AS IRAK4 INHIBITOR Russian patent published in 2023 - IPC C07D513/04 C07D519/00 A61K31/5377 A61K31/551 A61K31/519 A61P29/00 

Abstract RU 2801942 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound represented by formula (III), where R1-R3, L1, L2, ring A are defined in the claims, and a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing it, and the use of the compound.

EFFECT: compound can be used for the preparation of a medicinal product for the treatment of diseases associated with IRAK4.

20 cl, 2 dwg, 7 tbl, 60 ex

Similar patents RU2801942C2

Title Year Author Number
FGFR INHIBITOR AND ITS MEDICAL USE 2018
  • Wang, Yikai
  • Zhang, Yang
  • Chen, Zhengxia
  • Chen, Linlin
  • Feng, Tao
  • Huang, Rongxin
  • Li, Qiu
  • Li, Deyao
  • Sun, Jikui
  • Xu, Yangyang
  • Li, Jie
  • Li, Jian
  • Chen, Shuhui
RU2771311C2
THIENODIAZEPINE DERIVATIVES AND THEIR USE 2018
  • Shen, Chunli
  • U, Chende
  • Lyu, Yun
  • Gun, Chzhen
  • Li, Tszyan
  • Chen, Shukhuej
RU2795005C2
S1P1 AGONIST AND ITS APPLICATION 2017
  • Wu, Lingyun
  • Zhang, Peng
  • Li, Jian
  • Chen, Shuhui
RU2754845C2
CONTAINING A SUBSTITUTE, WHICH IS BUTANE, IN THE HETEROCYCLIC RING A PYRIDONE DERIVATIVE FOR TREATING FIBROSIS AND INFLAMMATORY DISEASES 2017
  • Shi Nen-Yan
  • Chen Bin
  • Chzhan Lej
  • Li Tszyan
  • Chen Shukhuej
RU2738844C2
MACROCYCLIC COMPOUND WITH FUNCTIONS OF WEE1 INHIBITOR AND ITS APPLICATION OPTIONS 2018
  • Qian, Wenyuan
  • Yang, Chundao
  • Li, Zhengwei
  • Li, Jie
  • Li, Jian
  • Chen, Shuhui
RU2783243C2
FUSED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF 2014
  • Xu Zusheng
  • Lou Yangtong
RU2663999C2
THIOPHENE COMPOUND, ITS PRODUCTION METHOD AND ITS PHARMACEUTICAL APPLICATION 2017
  • Wang, Jianfei
  • Zhang, Yang
  • Zhu, Wenyuan
  • Chen, Shuhui
RU2709473C1
CDK4/6 INHIBITOR 2017
  • Xu Zhaobing
  • Hu Lihong
  • Ding Charles Z.
  • Chen Shuhui
RU2747311C2
2,3-DIHYDRO-1H-PYRROLISINE-7-FORMAMIDE DERIVATIVE AND ITS APPLICATIONS 2019
  • Khe, Khajin
  • Sya, Tszyankhua
  • Gun, Chzhen
  • Li, Tszyan
  • Chen, Shukhuej
RU2792726C2
BORATE DERIVATIVE OF AZETIDINE 2019
  • Syun, Tszyan
  • Se, Chen
  • Syuj, Syunbin
  • Chen, Kevin S
  • Li, Tszyan
  • Chen, Shukhuej
  • Chzhan, Ajmin
  • Chzhan, Sitsyuan
  • Tyan, Sin
RU2802287C2

RU 2 801 942 C2

Authors

Chzhan, Yan

Van, Tszyanfej

Tan, Khajchzhun

Li, Tsze

Li, Tszyan

Chen, Shukhuej

Dates

2023-08-21Published

2019-06-25Filed