FIELD: chemistry.
SUBSTANCE: invention relates to a compound of formula (I)
,
where T is selected from N; R1 is selected from H or C1-6alkyl; each of R2, R3 is independently selected from H, C1-6alkyl or phenyl; or R2 and R3 are interconnected to form C3-6cycloalkyl; R4 is selected from H, F, Cl, Br, I or C1-3alkyl; R5 is selected from H; R6 is selected from H, F, Cl, Br, I or C1-3alkyl; or R5 and R6 are interconnected to form C3-6cycloalkyl or 5-6-member heterocycloalkyl, each of which is optionally substituted with 1, 2 or 3 R; wherein the number of heteroatoms in 5-6-member heterocycloalkyl is selected from 1–3, wherein the heteroatom is O; L is selected from a single bond, -C(=O)NH-; L1 is selected from a single bond, -NH-; R7 is selected from H or selected from a group consisting of C3-6cycloalkyl, phenyl and 5-6-member heteroaryl, each of which is optionally substituted with 1, 2 or 3 R; wherein the number of heteroatoms in 5-6-member heteroaryl is selected from 1–3, wherein the heteroatom is N; R is selected from F, Cl, Br, I, OH, N, N'-di(C1-2 alkyl)amino, C1-3 alkyl-NH-, C1-3 alkyl-O-, C1-3 alkyl-S(=O)2- or C1-6alkyl, which is optionally substituted with 1, 2 or 3 R'; R 'is selected from F, Cl, Br or I; and fragment 
selected from 
, used as a uric acid transporter (URAT1) inhibitor, specifically for preparing a pharmaceutical product for treating hyperuricemia and arthritis.
EFFECT: proposed are thiophene compound, its production method and its pharmaceutical application.
19 cl, 5 tbl
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