FIELD: pharmaceuticals.
SUBSTANCE: invention relates to compounds of general formula (I) and pharmaceutically acceptable salts thereof, where in formula (I) X is O; R2 is F, Cl, Br, I, OH, COOH or C1-6alkyl; R3 is H; R4 denotes F, Cl, Br, I or C1-6alkyl; ring A is selected from phenyl, thienyl, thiazolyl and benzothienyl; m and n are 1; p is 0 or 1. Invention also relates to a pharmaceutical composition for treating idiopathic pulmonary fibrosis or hepatic fibrosis and use of compounds of formula (I) or a pharmaceutical composition based thereon for preparing a medicament.
EFFECT: technical result is pyridone derivatives of formula (I) for treating idiopathic pulmonary fibrosis or hepatic fibrosis.
8 cl, 6 tbl, 5 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| THIOPHENE COMPOUND, ITS PRODUCTION METHOD AND ITS PHARMACEUTICAL APPLICATION | 2017 |
|
RU2709473C1 |
| PDE4 INHIBITOR | 2017 |
|
RU2743126C2 |
| COMPOUNDS BASED ON ISOTHIAZOLO[5,4-d]PYRIMIDINE AS IRAK4 INHIBITOR | 2019 |
|
RU2801942C2 |
| THIAZOLACTAM COMPOUNDS AS ERK INHIBITORS AND THEIR APPLICATIONS | 2020 |
|
RU2805569C1 |
| FGFR INHIBITOR AND ITS MEDICAL USE | 2018 |
|
RU2771311C2 |
| TRICYCLIC COMPOUNDS AFFECTING CRBN PROTEINS | 2019 |
|
RU2801068C2 |
| SPIRO COMPOUNDS AS ERK INHIBITORS AND THEIR USE | 2020 |
|
RU2800042C1 |
| MACROCYCLIC COMPOUND WITH FUNCTIONS OF WEE1 INHIBITOR AND ITS APPLICATION OPTIONS | 2018 |
|
RU2783243C2 |
| DERIVATIVE WITH CONDENSED RING AS A RECEPTOR INHIBITOR | 2018 |
|
RU2748993C1 |
| NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES AND USE THEREOF IN MEDICINAL PREPARATIONS | 2014 |
|
RU2694254C1 |
