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(19)

RU

(11)

2 802 215

(13)

C2

(51)

IPC

A61K38/27(2006-01-01)

A61K47/60(2017-01-01)

A61P5/06(2006-01-01)

(21) (22)

Application

2019114484, 2019-05-14

(24)

Start date

2009-04-29

(22)

Actual filing date

2019-05-14

(45)

Published

2023-08-23

(72)

Inventor

Rau, KharaldKindermann, ZuzanneLessmann, TorbenRasmussen, Grete NerskovKherzel, UlrikhVegge, TomasSprogee, Kennet

(73)

Holder

Astsendis Farma Endokrinolodzhi Divizhn A/S

PHARMACEUTICAL COMPOSITION AND A METHOD OF TREATMENT OF GROWTH HORMONE-RELATED DISEASES IN HUMANS Russian patent published in 2023 - IPC A61K38/27 A61K47/60 A61P5/06 

Abstract RU 2802215 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to recombinant human growth hormone (rhGH) prodrug conjugates, wherein the molecular weight of the prodrug without hGH-NH is at least 30 kDa and a maximum is 120 kDa. Also a method of treatment of diseases associated with growth hormone in humans using the above-described conjugates is described.

EFFECT: obtaining a pharmaceutical composition and a method of treatment of growth hormone-related diseases in humans.

9 cl, 11 dwg, 27 ex, 2 tbl

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RU 2 802 215 C2

Authors

Rau, Kharald

Kindermann, Zuzanne

Lessmann, Torben

Rasmussen, Grete Nerskov

Kherzel, Ulrikh

Vegge, Tomas

Sprogee, Kennet

Dates

2023-08-23—Published

2019-05-14—Filed

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