FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions relates to medicine and deals with a pharmaceutical composition for stimulation of growth and reproduction of cells in humans and other animals, which contains suitable pharmaceutical fillers and contains polyethyleneglycol-containing conjugate of the human growth hormone prodrug. The group of inventions also relates to a method of obtaining the said conjugate.
EFFECT: group of inventions provides longer activity of rhGH in comparison with non-modified rhGH, which makes it possible to reduce a dose and a mode of introduction, and reduce a level of lipoatrophy.
13 cl, 27 ex, 11 dwg, 2 tbl
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