FIELD: biotechnology.
SUBSTANCE: modified polypeptide with citrate synthase activity, where the amino acid corresponding to position 312 from the N-terminus of the polypeptide, consisting of the amino acid sequence of SEQ ID NO: 1 is replaced by another amino acid. The invention also relates to a modified polypeptide having citrate synthase activity and having a sequence homology of 80% or more and less than 100% with the amino acid sequence of SEQ ID NO: 1, where the amino acid corresponding to position 312 from the N-terminus of the polypeptide, consisting of the amino acid sequence of SEQ ID NO: 1 is replaced by another amino acid.
EFFECT: invention makes it possible to effectively obtain an L-amino acid using a microorganism containing one of the said modified polypeptides.
14 cl, 15 tbl, 8 ex
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