FIELD: medicine.
SUBSTANCE: invention relates to a method of treating an autoimmune disorder. The following provided: a method of treating a subject suffering from an autoimmune disorder, comprising administering to the said subject in need thereof a therapeutically effective amount of a PRMT5 inhibitor, wherein PRMT5 inhibitor is (1S,2S,3S,5R)-3-((6-(difluoromethyl)- 5-fluoro-1,2,3,4-tetrahydroiso-quinolin-8-yl)oxy)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-cyclopentan-1,2-diol:
or a pharmaceutically acceptable salt thereof, wherein the said subject is administered a therapeutically effective amount of 0.5 mg to 120 mg.
EFFECT: use of the method is effective for the treatment of an autoimmune disorder such as psoriasis in particular.
21 cl, 1 ex, 4 dwg
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