FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a diarylthiohydantoin compound of formula (I), where R1, T, rings A and B are defined in the claims, as an androgen receptor antagonist or a pharmaceutically acceptable salt thereof, to a pharmaceutical composition containing the compound, and to its use in the treatment of cellular proliferative disease mediated by androgens.
EFFECT: compound of the present application has a good androgen receptor antagonistic effect and excellent antitumor effect.
20 cl, 7 tbl, 80 ex
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Authors
Dates
2023-09-26—Published
2018-08-07—Filed